The Foundation for Liver and Gastrointestinal Research (SLO) was founded in 1985 as an institution without purpose of gain.
SLO's mission is to stimulate scientific research in the field of diseases of the liver and the gastrointestinal (GI) tract. To this aim it supports research into the prevention and treatment of liver and GI disease, as well as in the field of liver surgery and liver transplantation, and organizes and facilitates meetings dedicated to new developments within these fields. The Foundation undertakes a major part of its activities in Erasmus MC in Rotterdam.   Furthermore, it is involved in projects partially performed in other hospitals and academic centers or countries, typically in a coordinating role.

What we do 
SLO is functioning as an important facilitator of scientific research. It does so through a Clinical Research Bureau (CRB) founded in 1990. The CRB has gained a great deal of knowledge and experience on designing and conducting research projects that meet international criteria as described in GCP (Good Clinical Practice), FDA and EU guidelines. The CRB monitors administrative procedures and maintains contacts with researchers in the Netherlands as well as abroad. Each project is handled in a consistent manner and an accountant strictly handles the financial administration. The annual accounts have been compiled by 216 accountants.

The research does not only involve clinical research but also other patient-bound and fundamental research. The SLO has coordinated large number of national and international studies of which the results are published in leading medical journals, such as the New England Journal of Medicine, The Lancet, Annals of Internal Medicine, Gastroenterology, Hepatology, Gut and Journal of Hepatology. Likewise, the SLO was of great importance in initiating a fundamental research program by, among other things, investing in laboratory equipment and recruiting promising scientists. This has resulted in a number of flourishing lines of fundamental research, for example on rejection after liver transplantation and the chronic viral diseases hepatitis B and C.

The SLO played a crucial part in setting up and further developing the Rotterdam Liver Transplantation program. This program has made Rotterdam the largest center for adult liver transplantation in the Netherlands. 

The SLO is also involved in organizing medical conferences and courses for medical doctors (in training) and scientists. The annual Erasmus Liver Day is one of the most important liver conferences in The Netherlands. Besides conferences for professionals, SLO also organizes meetings for patients and their families. In 2019, the last meeting took place in congress center De Doelen in Rotterdam, with more than 300 participants.
Furthermore, the Mark van Blankenstein-SLO award is awarded annually to a medical student who performed excellent scientific research in the field of gastroenterology and hepatology. Also, every other year, the Solko W. Schalm award is awarded to someone who has been of great significance in the field of hepatology. 

Who we are 
The SLO Board consists of academic researchers working at the Erasmus MC (University Medical Center, Rotterdam): 
Dr. P.A. Boonstra, immunologist
Prof.dr. M.J. Bruno, gastroenterologist and hepatologist
Dr. C.M. den Hoed, gastroenterologist and hepatologist
Dr. R.J. de Knegt, gastroenterologist and hepatologist
Dr. A.D. Koch, gastroenterologist and hepatologist
Prof.dr. R.A. de Man, gastroenterologist and hepatologist 
Dr. A.J.P. van der Meer, gastroenterologist and hepatologist 
Dr. M.J. Sonneveld, gastroenterologist and hepatologist
Dr. V.M.C.W. Spaander, gastroenterologist and hepatologist
Prof.dr. C.J. van der Woude, gastroenterologist and hepatologist

The Supervisory Board consists of Prof.dr. H.W. Tilanus, Mr. H.M.I.Th. Breedveld and Mr. J.H. van Dorp. The members of the Board and the Supervisory Board are not financially compensated for their SLO activities.